Discovery of a broad-spectrum monoclonal antibody recognizing a conserved, linear epitope WFYDGYPT on VP1 protein of Enterovirus A species
The results suggest that the mAb 1H4 may be a useful tool for development with a cost-effective and accurate method for surveillance and early differentiation of serotypes from Enterovirus A species to other species.
Authors
- Lie Fu
- Ze-Jun Wang
- Rui-Lun Liu
- Shasha Qian
- Wei-Ping Jin
- Chen Wang (ORCID: https://orcid.org/0000-0003-3778-2782)
- Wenhui Wang (ORCID: https://orcid.org/0000-0001-6681-1373)
- Shengli Meng (ORCID: https://orcid.org/0000-0003-3183-9506)
- Jing Guo (ORCID: https://orcid.org/0000-0002-1133-3260)
- Mengjun Wang
- Shuo Shen (ORCID: https://orcid.org/0000-0002-8378-3770)
- Xiaoqi Chen (ORCID: https://orcid.org/0000-0001-7334-9981)
- Ya-Xin Du
- Song-Zhuang Li
Institutions
- Ajinomoto (United States) (US)
- Wuhan Institute of Bioengineering (CN)
- Zhejiang Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1186/s12985-024-02596-4
- Citations
- 1
- Primary Topic
- Viral Infections and Immunology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.40
Funders
- Ministry of Science and Technology of the People's Republic of China
- Science and Technology Development Center, Ministry of Education