Genome‐wide association study on chronic postsurgical pain after abdominal surgeries in the <scp>UK</scp> Biobank
This study provides preliminary evidence for genetic risk factors implicated in chronic postsurgical pain following abdominal surgery, particularly the PDE4D gene, which has been associated with pain in previous studies. The findings add to evidence suggesting potential for the future development of a clinically applicable tool for personalised risk prediction, aiding clinicians in stratifying patients and enhancing clinical decision-making through individualised risk assessments.
Authors
- Masja K. Toneman (ORCID: https://orcid.org/0000-0002-2674-0635)
- Richard P. G. ten Broek (ORCID: https://orcid.org/0000-0002-4012-7968)
- Kris C. P. Vissers (ORCID: https://orcid.org/0000-0002-2919-6356)
- Regina L. M. van Boekel (ORCID: https://orcid.org/0000-0002-0962-2944)
- Song Li (ORCID: https://orcid.org/0000-0002-1429-3161)
- Marieke J. H. Coenen (ORCID: https://orcid.org/0000-0001-8796-2031)
- Judith Petronella Maria Mangnus
- Stefano Strocchi
Institutions
- HAN University of Applied Sciences (NL)
- Radboud University Nijmegen (NL)
- Erasmus MC (NL)
- Radboud University Medical Center (NL)
Publication Details
- Journal
- Anaesthesia
- Published
- 2024-12-29
- DOI
- https://doi.org/10.1111/anae.16528
- Citations
- 3
- Primary Topic
- Anesthesia and Pain Management
- Type
- article
- Field-Weighted Citation Impact
- 1.72
Funders
- China Scholarship Council