Synaptophysin Positive Pulmonary Glomus Tumor Mimics Carcinoid Tumor on Fine‐Needle Aspiration

Glomus tumors are benign vascular soft tissue neoplasms of glomus bodies. Primary lung glomus tumors are rare and usually express smooth muscle markers, and are negative for cytokeratin and neuroendocrine markers in immunohistochemistry. We report a case of a primary lung glomus tumor showing diffuse, strong, aberrant immunoexpression for synaptophysin and morphologically mimicking a low-grade neuroendocrine tumor (carcinoid tumor).

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Publication Details

Journal
Diagnostic Cytopathology
Published
2024-12-29
DOI
https://doi.org/10.1002/dc.25439
Citations
1
Primary Topic
Soft tissue tumors and treatment
Type
article
Field-Weighted Citation Impact
0.42
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article

Synaptophysin Positive Pulmonary Glomus Tumor Mimics Carcinoid Tumor on Fine‐Needle Aspiration

Brant G. Wang, Maheshwari Ramineni, Nilanjana Sur, Roshan Raza et al.
1 citations
Diagnostic Cytopathology
Soft tissue tumors and treatment
0.42
article

Synaptophysin Positive Pulmonary Glomus Tumor Mimics Carcinoid Tumor on Fine‐Needle Aspiration

Brant G. Wang, Maheshwari Ramineni, Nilanjana Sur, Roshan Raza, Yuan Shen, Celia Marginean
article en
1 citations

Abstract

Glomus tumors are benign vascular soft tissue neoplasms of glomus bodies. Primary lung glomus tumors are rare and usually express smooth muscle markers, and are negative for cytokeratin and neuroendocrine markers in immunohistochemistry. We report a case of a primary lung glomus tumor showing diffuse, strong, aberrant immunoexpression for synaptophysin and morphologically mimicking a low-grade neuroendocrine tumor (carcinoid tumor).

Diagnostic CytopathologyVol. 53(4)
Baylor College of Medicine (US), St. Luke's Hospital (US), St. Luke's Hospital (US)
Good health and well-being
Openalex Percentile: Top 31%
Soft tissue tumors and treatment
0.42
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