Factors associated with oxidative stress in virologically suppressed people living with HIV on long-term antiretroviral therapy
Virologically suppressed PLWH on long-term ART showed a marked OS. Female sex, the exposure to PIs, and HCV co-infection were associated with higher oxidants, while higher HDL levels were linked to better antioxidant capacity. Interestingly, dual therapy, especially INSTI-based regimens, was associated with lower oxidative stress compared to triple therapy.
Authors
- Massimiliano Fabbiani (ORCID: https://orcid.org/0000-0002-1343-812X)
- Alberto Borghetti (ORCID: https://orcid.org/0000-0002-7910-021X)
- Elena Visconti
- Simone Belmonti (ORCID: https://orcid.org/0000-0003-3911-6652)
- Francesca Lombardi (ORCID: https://orcid.org/0000-0001-5757-8346)
- Pierluigi Francesco Salvo (ORCID: https://orcid.org/0000-0001-7559-7364)
- Valentina Iannone (ORCID: https://orcid.org/0000-0002-0751-8836)
- Alessia Sanfilippo
- Simona Di Giambenedetto
Institutions
- University of Siena (IT)
- Università Cattolica del Sacro Cuore (IT)
- University of Pisa (IT)
- Agostino Gemelli University Polyclinic (IT)
- Azienda Ospedaliera Universitaria Senese (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- AIDS Research and Therapy
- Published
- 2024-12-29
- DOI
- https://doi.org/10.1186/s12981-024-00694-5
- Citations
- 4
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.76
Funders
- Gilead Sciences