Disentangling the genetic overlap between ischemic stroke and obesity
Our study uncovered a significant genetic correlation and identified shared risk SNPs between BMI and IS. The identification of CHAF1A, CEP192, ULK4, CYP2D6, AS3MT, and WARS2 as potential functional genes common to both obesity and IS enriched our understanding of their genetic interplay, potentially advanced our grasp of their pathogenesis and therapeutic targets.
Authors
- Feng Han (ORCID: https://orcid.org/0009-0002-7449-6750)
- T. M. Zhang
- Yang Ren
Institutions
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2024-12-30
- DOI
- https://doi.org/10.1186/s13098-024-01555-x
- Citations
- 5
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 2.75
Funders
- Health Commission of Guizhou Province