Pituitary abnormalities in patients with pediatric growth hormone deficiency in a single tertiary center

The sensitivity and specificity of each cutoff value of IGF-1, IGF-1 SDS, IGFBP3, and GH peak levels were good and statistically significant in predicting brain MRI abnormalities. However, it was insufficient to predict all brain abnormalities with these variables. Therefore, we would like to recommend performing a brain MRI if a child is diagnosed with GHD.

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Publication Details

Journal
Annals of Pediatric Endocrinology & Metabolism
Published
2024-12-30
DOI
https://doi.org/10.6065/apem.2448070.035
Primary Topic
Growth Hormone and Insulin-like Growth Factors
Type
article
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article

Pituitary abnormalities in patients with pediatric growth hormone deficiency in a single tertiary center

Jeesuk Yu, Jeong Rye Kim, Hyeon Jun Jung
Annals of Pediatric Endocrinology & Metabolism
Growth Hormone and Insulin-like Growth Factors
article

Pituitary abnormalities in patients with pediatric growth hormone deficiency in a single tertiary center

Jeesuk Yu, Jeong Rye Kim, Hyeon Jun Jung
article en

Abstract

The sensitivity and specificity of each cutoff value of IGF-1, IGF-1 SDS, IGFBP3, and GH peak levels were good and statistically significant in predicting brain MRI abnormalities. However, it was insufficient to predict all brain abnormalities with these variables. Therefore, we would like to recommend performing a brain MRI if a child is diagnosed with GHD.

Annals of Pediatric Endocrinology & MetabolismVol. 29(6)
Dankook University Hospital (KR)
Good health and well-being
Openalex Percentile: Top 62%
Growth Hormone and Insulin-like Growth Factors
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