Association of stromal tumor-infiltrating lymphocytes with clinicopathological parameters in endometrial cancer

The findings suggest that high TIL infiltration correlates with favorable tumor characteristics, potentially serving as a prognostic marker for early and less aggressive EC. High TILs were associated with better tumor stage, grade, and reduced nodal involvement, indicating their protective role in tumor progression. However, the lack of association with certain parameters calls for further investigation into the functional state of TILs and their interactions within the tumor microenvironment.

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Publication Details

Journal
Korean Journal of Clinical Oncology
Published
2024-12-30
DOI
https://doi.org/10.14216/kjco.24010
Citations
2
Primary Topic
Endometrial and Cervical Cancer Treatments
Type
article
Field-Weighted Citation Impact
1.17
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article

Association of stromal tumor-infiltrating lymphocytes with clinicopathological parameters in endometrial cancer

Akansha Dubey, Sufian Zaheer, Sana Ahuja
2 citations
Korean Journal of Clinical Oncology
Endometrial and Cervical Cancer Treatments
1.17
article

Association of stromal tumor-infiltrating lymphocytes with clinicopathological parameters in endometrial cancer

Akansha Dubey, Sufian Zaheer, Sana Ahuja
article en
2 citations

Abstract

The findings suggest that high TIL infiltration correlates with favorable tumor characteristics, potentially serving as a prognostic marker for early and less aggressive EC. High TILs were associated with better tumor stage, grade, and reduced nodal involvement, indicating their protective role in tumor progression. However, the lack of association with certain parameters calls for further investigation into the functional state of TILs and their interactions within the tumor microenvironment.

Korean Journal of Clinical OncologyVol. 20(2)
Vardhman Mahavir Medical College & Safdarjung Hospital (IN)
Openalex Percentile: Top 18%
Endometrial and Cervical Cancer Treatments
1.17
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