Design and Cytotoxicity Evaluation of a Cancer-targeting Immunotoxin Based on a Camelid Nanobody-PE Fusion Protein.
These immunotoxin structures showed therapeutic potential against GRP78-expressing cancers, making them suitable candidates for targeted therapy pending in vivo studies.
Authors
- Mona Khoshbakht (ORCID: https://orcid.org/0000-0003-0113-3473)
- Hossein Aghamollaei (ORCID: https://orcid.org/0000-0003-4275-8613)
- Jafar Amani (ORCID: https://orcid.org/0000-0002-5155-4738)
- Mohammad Mahdi Forghanifard (ORCID: https://orcid.org/0000-0002-7691-6897)
Institutions
- Baqiyatallah University of Medical Sciences (IR)
- Islamic Azad University, Damghan Branch (IR)
Publication Details
- Journal
- PubMed
- Published
- 2024-12-31
- DOI
- https://doi.org/10.22034/iji.2024.104052.2878
- Citations
- 2
- Primary Topic
- Monoclonal and Polyclonal Antibodies Research
- Type
- article
- Field-Weighted Citation Impact
- 0.81