Transcranial alternating current stimulation inhibits ferroptosis and promotes functional recovery in spinal cord injury via the cGMP-PKG signalling pathway
Our findings suggest that tACS inhibits ferroptosis and necrotic degeneration by modulating the cGMP-PKG signalling pathway. This highlights the importance of tACS in promoting neural repair and functional recovery in SCI patients. Overall, tACS emerges as a highly effective and cost-efficient rehabilitative approach for SCI, offering new hope for improving patient outcomes.
Authors
- Haidi Bi
- Wansong Wang
- Ke Huang
- Weiming Sun
- Shining Xiao (ORCID: https://orcid.org/0000-0001-7600-8525)
- Guodong Zhang (ORCID: https://orcid.org/0009-0003-4230-0255)
- Lang Shuai
- Jing Fang
Institutions
- First Affiliated Hospital of Jiangxi Medical College (CN)
Publication Details
- Journal
- Life Sciences
- Published
- 2024-12-29
- DOI
- https://doi.org/10.1016/j.lfs.2024.123341
- Citations
- 5
- Primary Topic
- Spinal Cord Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 2.12