ANALYSIS OF THE ASSORTMENT OF COMBINED ORAL CONTRACEPTIVES REGISTERED ON THE PHARMACEUTICAL MARKET OF UKRAINE AND ASSESSMENT OF THEIR SOCIO-ECONOMIC AVAILABILITY

Combined oral contraceptives (COCs) are a group of medications widely used by women of reproductive age worldwide that contain progestin and estrogen or progestin alone. COCs remain one of the most common contraceptive methods used by women of reproductive age, with approximately 151 million users worldwide. The aim of the work was to research the range of combined oral contraceptives (COC) registered on the pharmaceutical market of Ukraine and to assess their socio-economic availability using the example of AKS Pharmacy No. 55 (Odesa, 162/2 Kostandi St.) for the year 2023. Research materials and methods. Analytical (data from the State Register of Medicinal Products and the search system tabletki.ua) and pharmacoeconomic (estimation of economic availability based on the indicator of adequacy of solvency Ca. s) research methods were used. Results and discussion. It was established that as of May 15, 2024, 36 trade names (TN) of COC preparations of foreign production were registered in Ukraine. The lion's share of the market is represented by IV generation COCs - 60% of the total assortment. 3rd, 2nd and 1st generation COCs account for 23, 14 and 3% of TN drugs, respectively. The type of composition containing only progestin is represented by 2 TN preparations. It was noted that among 12 TN COC drugs - "Regulon No. 3*21" tablets; "Femoston 1/10 No. 56" tablets and "Rygevidon No. 63" tablets belong to the middle range (Ca. s. = 6,5-7,5 %). All the other 9 TN COCs belong to the high range (Ca. s. less than 5 %). Conclusions. The range of combined oral contraceptives registered in the pharmaceutical market of Ukraine is completely provided by imported manufacturers, and according to the results of socio-economic availability of COCs it was established that these drugs belong to the category of high and medium availability.