ANALYSIS OF REGIONALLY METASTATIC CERVICAL CANCER ACCORDING TO DATA FROM THE SAMARKAND REGION OF THE REPUBLIC OF UZBEKISTAN

Today, cervical cancer is the most important global medical and social problem. Purpose of the study. To study the incidence of cervical cancer and analyze the results of treatment of stage III-IV disease in the Samarkand region. Material and methods. The study was conducted on the basis of the Samarkand branch of the Republican Specialized Scientific and Practical Medical Center of Oncology and Radiology of the Republic of Uzbekistan. The collection of research data included analysis of outpatient cards and anamnesis of patients admitted with the diagnosis of regionally metastasized forms of cervical cancer, data of patients with malignant neoplasms and advanced cases of malignant neoplasms - an accounting and reporting form. Interpretation work was carried out by age categories. At the same time, data from histologic and cytologic reports in the control group of cervical cancer stages III - IV, treated between 2020 and 2022, were used and processed. Results of the study. The reason for the first visit to the gynecologist at the time of diagnosis is mainly pain in the lower abdomen and lower back, bloody discharge from the genital tract on non-menstrual days and after contact, which are signs of advanced disease. The obstetric history revealed that 56 (53.3%) women did not consult a gynecologist at all after their last childbirth, and all patients had one to five medical abortions. Thirty-eight (36.2%) patients of early reproductive age were registered with an endocrinologist with a diagnosis of diffuse goiter. In 46% of the patients the menarche occurred at the age of 12-13 years, in 50% of the patients at the age of 14-16 years, and in 4% at the age of 18-19 years. Conclusion. The main goal of modern radiotherapy for cervical cancer today is radiation therapy without complications, elimination of relapse, and prolongation of survival. Our research continues in this direction.