Elevated neurofilament light chain associated with cobalt/chromium metal neurotoxicity in a patient with a failed hip implant
Serum NfL is elevated in a patient exhibiting neurotoxicity from Co/Cr implant exposure. The potential utility of serum NfL as a biomarker for metal associated neurotoxicity should be further explored.
Authors
- Danting Liu (ORCID: https://orcid.org/0000-0002-8662-5305)
- John A. Miller (ORCID: https://orcid.org/0009-0003-8145-1849)
- Sarah A Erdahl (ORCID: https://orcid.org/0000-0001-8330-789X)
- Paul J. Jannetto (ORCID: https://orcid.org/0000-0002-5629-439X)
- Alicia Algeciras‐Schimnich (ORCID: https://orcid.org/0000-0002-4455-6217)
- Joshua A. Bornhorst (ORCID: https://orcid.org/0009-0003-9297-3271)
- Jason S. Lipof
- Daniel J. Figdore (ORCID: https://orcid.org/0000-0002-4776-3203)
- Susan L. Ashrafzadeh Kian
Institutions
- Mayo Clinic (US)
- WinnMed (US)
- Stanford University (US)
Publication Details
- Journal
- Clinica Chimica Acta
- Published
- 2024-12-28
- DOI
- https://doi.org/10.1016/j.cca.2024.120118
- Citations
- 1
- Primary Topic
- Orthopaedic implants and arthroplasty
- Type
- article
- Field-Weighted Citation Impact
- 0.57