BORON-CONTAINING BIOACTIVE GLASS FOR MEDICAL USE

In this work, we investigated «in vitro» properties of boron-containing glass based on «Bioglass 45S5» by pyrolysis method of a liquid organic phase. It was found that 15 wt. % B2O3 bioglass has improved characteristics compared to the original composition. The inclusion of B2O3 in the composition of the material allows to reduce alkalization of the environment and the degradation rate of bioglass 45S5. Doping does not suppress the bioactivity of the material. The cytotoxicity of boron-containing glass is comparable to that of 45S5 glass. This indicates the safety of its use in medicine. The obtained material is intended to create bioactive coatings on implants, as well as fillers for various materials to impart bioactive, antibacterial and antibiofilm properties to them. The composition holds promise for bone implantology in modern medicine.