Real-world multicentre cohort study on choices and effectiveness of immunotherapies in NMOSD and MOGAD

This study provides insights into the evolving treatment landscape and effectiveness of immunotherapies in NMOSD and MOGAD. Established off-label therapies continue to play an important role, especially for patients with stable disease, with emerging evidence supporting newly approved therapies. Future studies are needed to refine treatment algorithms and address the ongoing uncertainties in MOGAD management.

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Publication Details

Journal
Journal of Neurology Neurosurgery & Psychiatry
Published
2024-12-27
DOI
https://doi.org/10.1136/jnnp-2024-334764
Citations
16
Primary Topic
Multiple Sclerosis Research Studies
Type
article
Field-Weighted Citation Impact
6.80

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article

Real-world multicentre cohort study on choices and effectiveness of immunotherapies in NMOSD and MOGAD

Franziska Bütow, Ingo Kleiter, Jan‐Patrick Stellmann, Brigitte Wildemann et al.
16 citations
Journal of Neurology Neurosurgery & Psychiatry
Multiple Sclerosis Research Studies
6.80
article

Real-world multicentre cohort study on choices and effectiveness of immunotherapies in NMOSD and MOGAD

Franziska Bütow, Ingo Kleiter, Jan‐Patrick Stellmann, Brigitte Wildemann, Makbule Şenel, Luisa Klotz, Carolin Schwake, Achim Berthele, Tania Kümpfel, Insa Schiffmann, Hayrettin Tumani, Matthias Grothe, Daria Tkachenko, Katrin Giglhuber, Ankelien Duchow, Paulus Stefan Rommer, Patrick Schindler, Marius Ringelstein, Thivya Pakeerathan, Orhan Aktaş, Judith Bellmann–Strobl, Joachim Havla, Friedemann Paul, Tim Friede, Corinna Trebst, Matthias Kaste, Martina Flaskamp, Vivien Häußler, Mirjam Korporal‐Kuhnke, Gero Lindenblatt, Jörn Peter Sieb, Klemens Angstwurm, Florian Then Bergh, Martin W. Hümmert, Sven Jarius, Mosche Pompsch, Jonathan Wickel, Daniel Engels, Mariella Herfurth, Eva Dawin, Ilya Ayzenberg, Lisa Revie, Hannah Pellkofer, Annette O. Walter, Markus Krämer, Katinka Fischer
article en
16 citations

Abstract

This study provides insights into the evolving treatment landscape and effectiveness of immunotherapies in NMOSD and MOGAD. Established off-label therapies continue to play an important role, especially for patients with stable disease, with emerging evidence supporting newly approved therapies. Future studies are needed to refine treatment algorithms and address the ongoing uncertainties in MOGAD management.

Journal of Neurology Neurosurgery & PsychiatryVol. 96(6)
Centre National de la Recherche Scientifique (FR), Universität Hamburg (DE), Universität Ulm (DE), Max Delbrück Center (DE), Heidelberg University (DE), University of Münster (DE), TUM Klinikum (DE), Medizinische Hochschule Hannover (DE), Universität Greifswald (DE), Humboldt-Universität zu Berlin (DE), University Medical Center Hamburg-Eppendorf (DE), Universitätsmedizin Göttingen (DE), Johanna-Etienne-Krankenhaus (DE), Herford Hospital (DE), Krankenhaus Nordwest (DE), Jena University Hospital (DE), St. Josef-Hospital (DE), Centre de Résonance Magnétique Biologique et Médicale (FR), Institute of Neuroimmunology of the Slovak Academy of Sciences (SK), University of Applied Sciences Stralsund (DE), Alfried Krupp Hospital (DE), Hôpital de la Timone (FR), Heinrich Heine University Düsseldorf (DE), University of Regensburg (DE), Freie Universität Berlin (DE), Medical University of Vienna (AT), Charité - Universitätsmedizin Berlin (DE), Ludwig-Maximilians-Universität München (DE), Ruhr University Bochum (DE), Leipzig University (DE)
AstraZeneca, Alexion Pharmaceuticals, Gemeinsame Bundesausschuss
Good health and well-being
Openalex Percentile: Top 3%
Multiple Sclerosis Research Studies
6.80
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