A Rare Case of Juvenile Granulosa Cell Tumor in a Premenarchal Female: Clinical Presentation, Diagnosis, and Management

Juvenile granulosa cell tumors (JGCTs), a rare type of ovarian tumor, are predominantly seen in premenarchal girls. We report a case of a 4.5-year-old girl with precocious puberty and a left ovarian JGCT, confirmed through imaging and histopathology. The patient underwent a fertility-sparing unilateral salpingo-oophorectomy, and no recurrence was observed after one year of follow-up. Surgery is the mainstay of treatment for early-stage JGCTs, and the role of adjuvant chemotherapy in advanced cases remains unclear. This report underscores the importance of early diagnosis and long-term monitoring in pediatric patients with ovarian masses.

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Journal
Cureus
Published
2024-12-28
DOI
https://doi.org/10.7759/cureus.76546
Citations
1
Primary Topic
Ovarian cancer diagnosis and treatment
Type
article
Field-Weighted Citation Impact
0.54
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A Rare Case of Juvenile Granulosa Cell Tumor in a Premenarchal Female: Clinical Presentation, Diagnosis, and Management

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article

A Rare Case of Juvenile Granulosa Cell Tumor in a Premenarchal Female: Clinical Presentation, Diagnosis, and Management

Elisavet Kanna, Ioannis Skondras, Zoi Lamprinou, Agelina Sfetsiori, Eleni Batsari
article en
1 citations

Abstract

Juvenile granulosa cell tumors (JGCTs), a rare type of ovarian tumor, are predominantly seen in premenarchal girls. We report a case of a 4.5-year-old girl with precocious puberty and a left ovarian JGCT, confirmed through imaging and histopathology. The patient underwent a fertility-sparing unilateral salpingo-oophorectomy, and no recurrence was observed after one year of follow-up. Surgery is the mainstay of treatment for early-stage JGCTs, and the role of adjuvant chemotherapy in advanced cases remains unclear. This report underscores the importance of early diagnosis and long-term monitoring in pediatric patients with ovarian masses.

CureusVol. 16(12)
National and Kapodistrian University of Athens (GR), Panagiotis & Aglaia Kyriakou Children's Hospital (GR)
Gender equality
Openalex Percentile: Top 24%
Ovarian cancer diagnosis and treatment
0.54
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