Integrating UPLC‐MS/MS Bioinformatics and In Vivo Experiments Validation to Elucidate the Mechanism of Wenzi Jiedu Decoction in Suppressing Colorectal Cancer

This study indicated that the potential mechanism of WJD in the prevention and treatment of CRC had the characteristics of the multi-target, multi-path, and multi-system mechanisms, which were mainly related to the regulation of chemokines and the promotion of apoptosis.

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Publication Details

Journal
Phytochemical Analysis
Published
2024-12-28
DOI
https://doi.org/10.1002/pca.3495
Primary Topic
Ferroptosis and cancer prognosis
Type
article
Field-Weighted Citation Impact
0.00

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article

Integrating UPLC‐MS/MS Bioinformatics and In Vivo Experiments Validation to Elucidate the Mechanism of Wenzi Jiedu Decoction in Suppressing Colorectal Cancer

Hongli Zhou, Tianqing Sang, Wenli Qiu, Alei Liang et al.
Phytochemical Analysis
Ferroptosis and cancer prognosis
article

Integrating UPLC‐MS/MS Bioinformatics and In Vivo Experiments Validation to Elucidate the Mechanism of Wenzi Jiedu Decoction in Suppressing Colorectal Cancer

Hongli Zhou, Tianqing Sang, Wenli Qiu, Alei Liang, Shi Lijing
article en

Abstract

This study indicated that the potential mechanism of WJD in the prevention and treatment of CRC had the characteristics of the multi-target, multi-path, and multi-system mechanisms, which were mainly related to the regulation of chemokines and the promotion of apoptosis.

Phytochemical AnalysisVol. 36(4)
Nanjing University of Chinese Medicine (CN), Nanjing Drum Tower Hospital (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 56%
Ferroptosis and cancer prognosis
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