Evaluating optic system compression in sellar tumors: A novel application of quantitative pupillometry

This study contributes to the field of skull base surgery by evaluating the utility of QP as a diagnostic tool for neurological assessment in patients with sellar region tumors. The findings suggest that QP may help in assessing the extent of tumor-related compression on the optic system. It particularly points to differences in the effects of optic chiasm and CN III compression, with observed variations in NPI scores corresponding to the type of compression in specific tumors, such as pituitary adenomas and tuberculum sellae meningiomas. By providing rapid and non-invasive assessments, QP supports enhanced correlation with clinical and radiological evaluations, potentially improving targeted interventions for these complex conditions.

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Publication Details

Journal
Acta Neurochirurgica
Published
2024-12-28
DOI
https://doi.org/10.1007/s00701-024-06401-7
Citations
3
Primary Topic
Glaucoma and retinal disorders
Type
article
Field-Weighted Citation Impact
1.62

Funders

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article

Evaluating optic system compression in sellar tumors: A novel application of quantitative pupillometry

Sandro M. Krieg, Daniel Kühlwein, Johannes Walter, Pavlina Lenga et al.
3 citations
Acta Neurochirurgica
Glaucoma and retinal disorders
1.62
article

Evaluating optic system compression in sellar tumors: A novel application of quantitative pupillometry

Sandro M. Krieg, Daniel Kühlwein, Johannes Walter, Pavlina Lenga, Martin Grutza, Christopher Beynon
article en
3 citations

Abstract

This study contributes to the field of skull base surgery by evaluating the utility of QP as a diagnostic tool for neurological assessment in patients with sellar region tumors. The findings suggest that QP may help in assessing the extent of tumor-related compression on the optic system. It particularly points to differences in the effects of optic chiasm and CN III compression, with observed variations in NPI scores corresponding to the type of compression in specific tumors, such as pituitary adenomas and tuberculum sellae meningiomas. By providing rapid and non-invasive assessments, QP supports enhanced correlation with clinical and radiological evaluations, potentially improving targeted interventions for these complex conditions.

Acta NeurochirurgicaVol. 166(1)
Heidelberg University (DE), University Hospital Heidelberg (DE), University Medical Centre Mannheim (DE), Heidelberg University (US)
Universitätsklinikum Heidelberg
Good health and well-being
Openalex Percentile: Top 15%
Glaucoma and retinal disorders
1.62
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Evaluating optic system compression in sellar tumors: A novel application of quantitative pupillometry — Sandro M. Krieg, Daniel Kühlwein, et al. · Acta Neurochirurgica (2024) | TGRS Research Map | TGRS