Impact of Race on the Outcomes of Retinoblastoma Treated With Primary Enucleation: A Global Study of 1426 Patients

The histopathological features in primarily enucleated eyes with retinoblastoma vary with race. Despite adjusting for tumour staging and adjuvant treatment, race remains an independent predictor of outcomes, including orbital tumour recurrence and metastasis-related death. A stringent follow-up and a more aggressive treatment approach is recommended in Asians and Hispanics who manifest high-risk histopathological features.

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Publication Details

Journal
Clinical and Experimental Ophthalmology
Published
2024-12-28
DOI
https://doi.org/10.1111/ceo.14488
Citations
1
Primary Topic
Ocular Oncology and Treatments
Type
article
Field-Weighted Citation Impact
0.54

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article

Impact of Race on the Outcomes of Retinoblastoma Treated With Primary Enucleation: A Global Study of 1426 Patients

Yacoub A. Yousef, Ido Didi Fabian, Maya Eiger‐Moscovich, Alia Ahmad et al.
1 citations
Clinical and Experimental Ophthalmology
Ocular Oncology and Treatments
0.54
article

Impact of Race on the Outcomes of Retinoblastoma Treated With Primary Enucleation: A Global Study of 1426 Patients

Yacoub A. Yousef, Ido Didi Fabian, Maya Eiger‐Moscovich, Alia Ahmad, Tatiana L. Ushakova, Mandeep S. Sagoo, M. Ashwin Reddy, Mona Mohammad, G. Baker Hubbard, Rosdali Díaz Coronado, Swathi Kaliki, Hans E. Grossniklaus, Vijitha S. Vempuluru, Sandra E. Staffieri, Mika Tanabe, Jesse L. Berry, Jacob Pe’er, Carol L. Shields
article en
1 citations

Abstract

The histopathological features in primarily enucleated eyes with retinoblastoma vary with race. Despite adjusting for tumour staging and adjuvant treatment, race remains an independent predictor of outcomes, including orbital tumour recurrence and metastasis-related death. A stringent follow-up and a more aggressive treatment approach is recommended in Asians and Hispanics who manifest high-risk histopathological features.

Clinical and Experimental OphthalmologyVol. 53(4)
Royal Children's Hospital (AU), Moorfields Eye Hospital NHS Foundation Trust (GB), Kyushu University (JP), Emory University (US), Tel Aviv University (IL), The University of Melbourne (AU), Universidad Peruana Cayetano Heredia (PE), Barts Health NHS Trust (GB), King Hussein Cancer Center (JO), Sheba Medical Center (IL), Hadassah Medical Center (IL), Keck Hospital of USC (US), L V Prasad Eye Institute (IN), Royal London Hospital (GB), University of Health Sciences Lahore (PK), Russian Cancer Research Center NN Blokhin (RU), Centre for Eye Research Australia (AU), Russian Medical Academy of Continuous Professional Education (RU), Instituto Nacional de Enfermedades Neoplásicas (PE), Murdoch Children's Research Institute (AU), Moorfields Eye Hospital (GB), University College London (GB), Wills Eye Hospital (US)
Hyderabad Eye Research Foundation
Good health and well-being
Openalex Percentile: Top 28%
Ocular Oncology and Treatments
0.54
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