Solvent Controlled Chemodivergent Sulfonyl Addition into Enynones: Synthesis of α-Furyl Sulfones and Stereodefined Vinyl Sulfones
Sodium salt of aryl sulfinic acid reacts with enynone in a different manner, yielding α-furyl sulfone and stereodefined vinyl sulfone in toluene and EtOH respectively in the presence of ZnCl<sub>2</sub>. The salient features of this protocol include chemoselectivity, broad substrate scope, high efficiency, high yield, and easy purification. The synthetic utilities of the products are demonstrated by cycloaddition and cis-trans photoisomerization reactions.
Authors
- Ganesh Chandra Nandi (ORCID: https://orcid.org/0000-0003-2159-8075)
- Ramesh Kataria (ORCID: https://orcid.org/0000-0002-4279-4801)
- Padma Priya V. R.
- Antony Haritha Mercy A
Institutions
- National Institute of Technology Tiruchirappalli (IN)
- Panjab University (IN)
Publication Details
- Journal
- The Journal of Organic Chemistry
- Published
- 2024-12-28
- DOI
- https://doi.org/10.1021/acs.joc.4c02165
- Citations
- 4
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 1.00
Funders
- Council of Scientific and Industrial Research, India