Cognitive and neurodegenerative trajectories of subjective cognitive decline according to baseline biomarkers: Results of the CoSCo study
This is part of a multicenter prospective cohort study in Korea. We investigated cognitive and atrophic trajectories in SCD over 24 months. High risk SCDs revealed greater cognitive decline and hippocampal atrophy. Integration of plasma and MRIs yielded better predictions than other categories. Risk stratification using plasma and MRIs can be used for screening and prognosis.
Authors
- Dong Won Yang (ORCID: https://orcid.org/0000-0002-4733-7298)
- Sung Min Kang (ORCID: https://orcid.org/0000-0003-1959-8578)
- Jee Hyang Jeong (ORCID: https://orcid.org/0000-0001-7945-6956)
- Sang-Yun Kim (ORCID: https://orcid.org/0000-0002-2952-5404)
- Min Jeong Wang (ORCID: https://orcid.org/0000-0001-7215-4883)
- Kee Hyung Park (ORCID: https://orcid.org/0000-0001-6847-6679)
- Yun Jeong Hong (ORCID: https://orcid.org/0000-0002-4996-4981)
- Seong Hye Choi (ORCID: https://orcid.org/0000-0002-4180-8626)
Institutions
- Ewha Womans University (KR)
- Inha University (KR)
- Seoul National University Bundang Hospital (KR)
- Gachon University Gil Medical Center (KR)
- The Catholic University of Korea Uijeongbu St. Mary's Hospital (KR)
- PeopleBio (South Korea) (KR)
- The Catholic University of Korea Seoul St. Mary's Hospital (KR)
- Catholic University of Korea (KR)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-28
- DOI
- https://doi.org/10.1002/alz.14473
- Citations
- 2
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.77
Funders
- National Research Foundation
- Ministry of Health and Welfare
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea