Disrupted brain networks underlying high‐fidelity memory retrieval in subjective cognitive decline: A task‐based fMRI study
Objective high-fidelity retrieval deficits detected in older adults with SCD. Dysfunctional neural activations within retrieval networks impair memory accuracy. Reduced task-based FC drives high-fidelity retrieval deficits. The SCD-related disruption of integrative function partly explains such deficits. Future studies may benefit from inspections on obstruction in cognitive process.
Authors
- Ke-Hang Xie
- Qinghe Zeng (ORCID: https://orcid.org/0000-0002-1473-8327)
- Wei Yieng Tang (ORCID: https://orcid.org/0000-0002-9901-4933)
- Juan Li (ORCID: https://orcid.org/0000-0002-7668-5996)
- Ying Han (ORCID: https://orcid.org/0000-0003-0377-7424)
- Xinhu Jin
- Xiaoyu Cui
Institutions
- Capital Medical University (CN)
- Hainan University (CN)
- National Clinical Research Center for Digestive Diseases (CN)
- Shenzhen Bay Laboratory (CN)
- Chinese Institute for Brain Research (CN)
- Institute of Psychology, Chinese Academy of Sciences (CN)
- Karamay Central Hospital of Xinjiang (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2024-12-28
- DOI
- https://doi.org/10.1002/alz.14431
- Citations
- 4
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.37
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China