Multidisciplinary approach to nasal squamous cell carcinoma: Merging clinical insights and imaging for enhanced management

Squamous cell carcinomas, or epidermoid carcinomas, while common in the skin, are exceedingly rare in the nasal cavity. This location presents a significant diagnostic challenge due to the region's complex anatomy and the heightened risk of severe complications. Here, we report the case of a 79-year-old male with a recurrence of epidermoid carcinoma in the left nasal antrum following prior radiotherapy. A thorough clinical and imaging evaluation, incorporating computed tomography (CT) and FDG-PET/CT, facilitated a multidisciplinary approach. This approach underscored the importance of early recognition of risk factors and close collaboration among radiology, oncology, and surgical specialties (otolaryngology, head and neck surgery, and oncologic surgery) to improve patient outcomes and minimize complications. This case highlights the critical role of timely diagnosis and rigorous follow-up in preventing recurrence, as well as the necessity of a collaborative strategy to manage this aggressive malignancy effectively, given its occurrence in such a delicate and anatomically significant region.