Cancer outcomes and cardiopulmonary toxicities for Black patients with breast cancer treated with proton therapy
Black women presenting for proton therapy had higher baseline risks of cardiovascular co-morbidities combined with more aggressive breast cancer biology and a subsequent 2.6-fold increased risk of pulmonary events after proton therapy. Our findings support the use of advanced radiation techniques as a means of sparing important organs at risk, especially in historically marginalized populations.
Authors
- Sravya Koduri (ORCID: https://orcid.org/0000-0002-8447-2456)
- Sarah Ruff
- Gurbani Singh
- Michael Kidorf (ORCID: https://orcid.org/0000-0002-6346-3315)
- Sarah McAvoy (ORCID: https://orcid.org/0000-0002-1114-4312)
- Akshar Patel (ORCID: https://orcid.org/0000-0002-2524-6061)
- Søren M. Bentzen (ORCID: https://orcid.org/0000-0002-7444-7564)
- Melissa A.L. Vyfhuis (ORCID: https://orcid.org/0000-0003-4612-7341)
- E.M. Nichols (ORCID: https://orcid.org/0000-0002-0411-3753)
- Malla Rao (ORCID: https://orcid.org/0000-0001-7193-188X)
Institutions
- University of Maryland, Baltimore (US)
- NYU Langone Health (US)
- Chesapeake Urology Associates (US)
Publication Details
- Journal
- JNCI Cancer Spectrum
- Published
- 2024-12-28
- DOI
- https://doi.org/10.1093/jncics/pkae129
- Citations
- 2
- Primary Topic
- Chemotherapy-induced cardiotoxicity and mitigation
- Type
- article
- Field-Weighted Citation Impact
- 0.80