NANOTECHNOLOGY IN EVOLUTION OF NANOSUSPENTION DRUG DELIVERY SYSTEM

Nanotechnology includes nanosuspensions.The term "nanosuspensions" refers to submicron colloidal dispersions of pharmaceutical active ingredient particles in a liquid phase with a size of less than 1 m and no matrix material.These dispersions are stabilized by polymers and surfactants.Nanosuspensions are distinct from both solid lipid and polymeric nanoparticles in that the former are lipid carriers of medications while the latter are polymeric colloidal carriers of drugs.All medications that are water insoluble can benefit from the easy preparation of nanosuspensions.Emulsion solvent evaporation, melt emulsification, high pressure homogenizer, wet mill and supercritical fluid processes are used to prepare nanosuspensions.Oral, parenteral, pulmonary and ophthalmic administration are available for nanosuspensions.Combined with ocular delivery systems nanosuspensions can also be utilized for targeted drug delivery.