Acute/baseline ratios of all 3 MC mediator metabolites can enhance diagnosis and management of mast cell activation syndrome
The value of measuring all 3 MC mediator metabolites during MCAS should not be overlooked. These measurements can facilitate the successful prevention of attacks. Furthermore, results from these tests show that histamine is often a minor player, whereas acute/baseline levels of the metabolites of LTC<sub>4</sub> and prostaglandin D<sub>2</sub> are frequently much higher, warranting nonantihistamine treatment.
Authors
- Andrew W. Taylor (ORCID: https://orcid.org/0000-0002-0330-8591)
- Joseph H. Butterfield
Institutions
- Mayo Clinic (US)
- Mayo Clinic Health System (US)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology Global
- Published
- 2024-12-28
- DOI
- https://doi.org/10.1016/j.jacig.2024.100399
- Citations
- 2
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 0.48