Deciphering glioblastoma pathogenesis: Insights from mitophagy dysregulation and SNX7 as a therapeutic target
Our results highlight the importance of mitophagy dysregulation in the pathogenesis of glioblastoma and identify SNX7 as a novel therapeutic target. Further research is needed to elucidate the underlying mechanisms of SNX7 in glioblastoma and validate its clinical significance. These findings may facilitate the development of personalized treatment strategies and improve outcomes for glioblastoma patients.
Authors
- Yuanxiang Lin (ORCID: https://orcid.org/0000-0001-5803-2644)
- Renfu Liu
- Wenzhong Mei
- Y Zhang (ORCID: https://orcid.org/0009-0004-6833-6480)
- Binghong Chen (ORCID: https://orcid.org/0000-0001-9090-3489)
Institutions
- Fujian Medical University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2024-12-28
- DOI
- https://doi.org/10.1016/j.brainresbull.2024.111184
- Primary Topic
- Autophagy in Disease and Therapy
- Type
- article
- Field-Weighted Citation Impact
- 0.00