Investigating the role of exosomal microRNA-5703 in modulating tumor-associated endothelial cells in lung cancer
miR-5703 operates as an oncogenic factor in lung cancer. After being taken up by TAECs, exosomal miR-5703 promotes angiogenesis, EndMT, and barrier damage by targeting ING4. Hence, miR-5703 is a potential target in the lung cancer microenvironment.
Authors
- Zhenfa Zhang (ORCID: https://orcid.org/0000-0002-2672-4416)
- Yuyu Liu (ORCID: https://orcid.org/0000-0002-4814-8616)
- Bing Wen (ORCID: https://orcid.org/0000-0001-9152-1511)
- Rancen Tao
Institutions
- Tianjin Medical University Cancer Institute and Hospital (CN)
- Second People’s Hospital of Yibin (CN)
Publication Details
- Journal
- CytoJournal
- Published
- 2024-12-27
- DOI
- https://doi.org/10.25259/cytojournal_99_2024
- Citations
- 9
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 2.10