Three new terpenoid derivatives from the deep-sea-derived fungus <i>Aspergillus sydowii</i> DFFSCS007

Three new terpenoid derivatives (1<i>S</i>,6<i>R</i>,7<i>S</i>)-hydrobenzosydowic acid (<b>1</b>), (1 <i>R</i>,6<i>S</i>,7<i>S</i>)-hydrobenzosydowic acid (<b>2</b>), and (7 <i>R</i>,10<i>R</i>)-11-dehydroxy-iso-10-hydroxysydowic acid (<b>3</b>), along with the known analogues (<i>S</i>)-2-(1-(4-nitrobenzoyl)pyrrolidine-2-carboxamido)benzoic acid (<b>4</b>) and trihydroxybutyl ester of 4-carboxydiorcinol (<b>5</b>) were isolated from the deep-sea-derived fungus <i>Aspergillus sydowii</i> DFFSCS007. Their structures were determined by spectroscopic analysis. Compound <b>4</b> with a nitrobenzene group was isolated from nature for the first time. The antibacterial activities of <b>1</b>-<b>5</b> and cytotoxicity of <b>1</b>-<b>3</b> were also evaluated.

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Publication Details

Journal
Journal of Asian Natural Products Research
Published
2024-12-28
DOI
https://doi.org/10.1080/10286020.2024.2443086
Citations
1
Primary Topic
Microbial Natural Products and Biosynthesis
Type
article
Field-Weighted Citation Impact
0.45
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article

Three new terpenoid derivatives from the deep-sea-derived fungus Aspergillus sydowii DFFSCS007

Ke-Yue Wu, Xiaopu Ren, Shu-Hua Qi
1 citations
Journal of Asian Natural Products Research
Microbial Natural Products and Biosynthesis
0.45
article

Three new terpenoid derivatives from the deep-sea-derived fungus Aspergillus sydowii DFFSCS007

Ke-Yue Wu, Xiaopu Ren, Shu-Hua Qi
article en
1 citations

Abstract

Three new terpenoid derivatives (1<i>S</i>,6<i>R</i>,7<i>S</i>)-hydrobenzosydowic acid (<b>1</b>), (1 <i>R</i>,6<i>S</i>,7<i>S</i>)-hydrobenzosydowic acid (<b>2</b>), and (7 <i>R</i>,10<i>R</i>)-11-dehydroxy-iso-10-hydroxysydowic acid (<b>3</b>), along with the known analogues (<i>S</i>)-2-(1-(4-nitrobenzoyl)pyrrolidine-2-carboxamido)benzoic acid (<b>4</b>) and trihydroxybutyl ester of 4-carboxydiorcinol (<b>5</b>) were isolated from the deep-sea-derived fungus <i>Aspergillus sydowii</i> DFFSCS007. Their structures were determined by spectroscopic analysis. Compound <b>4</b> with a nitrobenzene group was isolated from nature for the first time. The antibacterial activities of <b>1</b>-<b>5</b> and cytotoxicity of <b>1</b>-<b>3</b> were also evaluated.

Journal of Asian Natural Products ResearchVol. 27(7)
Chinese Academy of Sciences (CN), Institute of Oceanology (CN), South China Sea Institute Of Oceanology (CN), University of Chinese Academy of Sciences (CN)
Life below water
Openalex Percentile: Top 29%
Microbial Natural Products and Biosynthesis
0.45
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Three new terpenoid derivatives from the deep-sea-derived fungus <i>Aspergillus sydowii</i> DFFSCS007 — Ke-Yue Wu, Xiaopu Ren, et al. · Journal of Asian Natural Products Research (2024) | TGRS Research Map | TGRS