Forensic Analysis and Removal of Date-Rape Drug Present in the Spiked Drinks

Abstract Background: Beverages play a positive role in a balanced diet. Beverages can provide an enjoyable and refreshing mind to reach a particular target. In beverages, date-rape drugs, such as Rohypnol, gamma-hydroxybutyric acid, and ketamine, were usually added to make victims to become weak, confused, unconscious, and vulnerable. Aims and Objectives: The aims and objectives of the research work are to analyze the beverages, viz., Sprite, Coca-Cola and Coffee by analytical techniques and to degrade the date-rape drug present in the beverages by photocatalysis using activated carbon as the photocatalyst material. Materials and Methods: The drug (clonazepam) and beverages used in the research work were analyzed using FTIR, UV and HPLC techniques. Results: From the FTIR, in beverages (Sprite and Coca-Cola), the peaks corresponding to C-O and O-H functional groups confirmed the presence of CO 2 and H 2 O and in Coffee, the presence of ν as (COC) and ν s (COC) vibration bands is found out. The UV-visible analysis confirmed the λ max value for activated carbon as 251 nm. Under visible light and activated carbon photocatalyst, 53.57% of drug molecule was degraded from coca cola which was found to be highest than other beverages. The degradation of drug molecule was also confirmed by the reduction in the peak area for a particular retention time through HPLC analysis. Conclusion: Photocatalysis can be effectively used to remove any drug present in the spike drinks.

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Publication Details

Journal
Journal of Forensic Science and Medicine
Published
2024-10-01
DOI
https://doi.org/10.4103/jfsm.jfsm_110_22
Primary Topic
Pharmaceutical Quality and Counterfeiting
Type
article
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article

Forensic Analysis and Removal of Date-Rape Drug Present in the Spiked Drinks

Manasai Arunkumar, M Prabha, Arputharaj Samson Nesaraj
Journal of Forensic Science and Medicine
Pharmaceutical Quality and Counterfeiting
article

Forensic Analysis and Removal of Date-Rape Drug Present in the Spiked Drinks

Manasai Arunkumar, M Prabha, Arputharaj Samson Nesaraj
article en

Abstract

Abstract Background: Beverages play a positive role in a balanced diet. Beverages can provide an enjoyable and refreshing mind to reach a particular target. In beverages, date-rape drugs, such as Rohypnol, gamma-hydroxybutyric acid, and ketamine, were usually added to make victims to become weak, confused, unconscious, and vulnerable. Aims and Objectives: The aims and objectives of the research work are to analyze the beverages, viz., Sprite, Coca-Cola and Coffee by analytical techniques and to degrade the date-rape drug present in the beverages by photocatalysis using activated carbon as the photocatalyst material. Materials and Methods: The drug (clonazepam) and beverages used in the research work were analyzed using FTIR, UV and HPLC techniques. Results: From the FTIR, in beverages (Sprite and Coca-Cola), the peaks corresponding to C-O and O-H functional groups confirmed the presence of CO 2 and H 2 O and in Coffee, the presence of ν as (COC) and ν s (COC) vibration bands is found out. The UV-visible analysis confirmed the λ max value for activated carbon as 251 nm. Under visible light and activated carbon photocatalyst, 53.57% of drug molecule was degraded from coca cola which was found to be highest than other beverages. The degradation of drug molecule was also confirmed by the reduction in the peak area for a particular retention time through HPLC analysis. Conclusion: Photocatalysis can be effectively used to remove any drug present in the spike drinks.

Journal of Forensic Science and MedicineVol. 10(4)
Karunya University (IN), Kalasalingam Academy of Research and Education (IN)
Openalex Percentile: Top 63%
Pharmaceutical Quality and Counterfeiting
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