Effects of <scp><i>Globularia cordifolia</i></scp> on colon cancer cells: antioxidant activity, inflammatory cytokine analysis and molecular docking studies
The findings indicate that G. cordifolia extract exhibits strong antioxidant, anti-inflammatory and antiproliferative properties, making it a promising biomolecular agent for colon cancer therapy. The high phenolic and flavonoid contents, combined with the bioactive compounds' interactions with key molecular targets, underscore its potential therapeutic applications. © 2024 Society of Chemical Industry.
Authors
- Alper Durmaz (ORCID: https://orcid.org/0000-0001-6927-3283)
- Özge Balpınar (ORCID: https://orcid.org/0000-0003-4235-9241)
- Emine İncilay Torunoğlu (ORCID: https://orcid.org/0000-0003-4641-0067)
- Muhammed Sait Ertuğrul (ORCID: https://orcid.org/0000-0002-7885-5645)
- Betül Aydın (ORCID: https://orcid.org/0000-0002-9092-1350)
- Gül Fatma Yarım (ORCID: https://orcid.org/0000-0003-4050-429X)
- Erdi Can Aytar (ORCID: https://orcid.org/0000-0001-6045-0183)
Institutions
- Artvin Coruh University (TR)
- Usak University (TR)
- Ondokuz Mayıs University (TR)
- Necmettin Erbakan University (TR)
- Gazi University (TR)
Publication Details
- Journal
- Journal of the Science of Food and Agriculture
- Published
- 2024-12-27
- DOI
- https://doi.org/10.1002/jsfa.14100
- Citations
- 1
- Primary Topic
- Phytochemicals and Antioxidant Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.22