IN VITRO EVALUATION OF ANTHELMINTIC ACTIVITY OF ETHANOLIC LEAF EXTRACT OF THESPESIA POPULNAE ON INDIAN EARTHWORMS EISENIELLA FETIDA

The purpose of the current study was to assess the effectiveness of the anthelmintic properties of the leaves of Thespesia populnae against Indian earthworms (Eiseniella fetida).With varying doses, Thespesia populnae ethanolic leaf extract was utilised to test on Eiseniella fetida for anthelmintic activity.The earthworms were categorized into 7 groups, with Saline serving as the control (Group 1), Albendazole serving as the standard at 2.5 mg/ml, 5 mg/ml, and 10 mg/ml (Group 2,3,4), and TPEE serving as the test drug at 2.5 mg/ml, 5 mg/ml, and 10 mg/ml (Groups 5, 6, and 7).The plant showed significant anthelmintic activity but less potent than the standard drug.The phytoconstituents may have an anthelmintic action, according to these findings.Tannins was detected in the alcoholic Thespesia populnae leaf extracts.Hence, presence of tannins might display anthelmintic activity of TPEE.TPEE displayed anthelmintic activity depending on the dose.