The ability of clostridium novyi-NT spores to induce apoptosis via the mitochondrial pathway in mice with HPV-positive cervical cancer tumors derived from the TC-1 cell line
The study's outcomes demonstrated that the introduction of Clostridium novyi-NT spores triggered apoptosis in cervical cancer cells (derived from the TC-1 cell line) via the mitochondrial pathway, subsequently resulting in tumor regression in a mouse model.
Authors
- Azita Dilmaghani (ORCID: https://orcid.org/0000-0001-6556-8332)
- Parisa Jamour
- Asghar Abdoli
- Behrouz Ebadi Sharafabad
Institutions
- Pasteur Institute of Iran (IR)
- Tabriz University of Medical Sciences (IR)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2024-12-28
- DOI
- https://doi.org/10.1186/s12906-024-04742-5
- Citations
- 4
- Primary Topic
- Cancer Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.55
Funders
- Tabriz University of Medical Sciences
- University of Tabriz