Emerging Trend of Central Precocious Puberty: A Retrospective Study of Cases Diagnosed Before and During the COVID-19 Pandemic in a Portuguese Tertiary-Level Hospital

This study revealed a significant four-fold increase in the diagnosis of ICPP during the pandemic, particularly among girls. Furthermore, in the pandemic group, thelarche onset was earlier, raising the question of whether increased parental presence at home contributed to heightened awareness of pubertal changes. Despite the challenges posed by the pandemic in terms of referrals and follow-up, these results point to efficient work that led to prompt treatment initiation without delays, unlike in other pathologies, as mainly observed in adults. Surprisingly, no significant increase in body mass index was observed, suggesting that other factors may be involved. To substantiate these findings and uncover additional potential contributing factors for the development of ICPP, a more extensive research effort is warranted.