[High expression of CRTAC1 promotes proliferation, migration and immune cell infiltration of gastric cancer by regulating the PI3K/AKT signaling pathway].
High expression of CRTAC1 in GC tissues affects immunotherapeutic efficacy and prognosis of the patients, possibly by promoting epithelial-mesenchymal transition <i>via</i> modulating tumor mutational load, tumor microenvironment, and the PI3K/AKT signaling pathway.
Authors
- Rui Dong (ORCID: https://orcid.org/0000-0002-8768-995X)
- Mulin Liu (ORCID: https://orcid.org/0000-0002-1566-5027)
- Guoqing Liu (ORCID: https://orcid.org/0000-0002-5428-1720)
- Weichen Lu
- Fei Lu (ORCID: https://orcid.org/0000-0002-4868-8946)
- Lei Gao (ORCID: https://orcid.org/0000-0002-3897-6362)
- Fu-Xing Zhang (ORCID: https://orcid.org/0000-0003-4243-8775)
- L. Gao
- Zhongkuo Zhao
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
- Fourth Affiliated Hospital of Anhui Medical University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- PubMed
- Published
- 2024-12-20
- DOI
- https://doi.org/10.12122/j.issn.1673-4254.2024.12.19
- Primary Topic
- Cancer Mechanisms and Therapy
- Type
- article