Dye amount quantification of Papanicolaou-stained cytological images by multispectral unmixing: spectral analysis of cytoplasmic mucin
Multispectral imaging enables the quantitative analysis of dye amount maps of Papanicolaou-stained cytology specimens. The effectiveness is demonstrated in interpreting and classifying the cytoplasmic mucin of EC and LEGH cells in cervical cytology.
Authors
- Masahiro Yamaguchi (ORCID: https://orcid.org/0000-0003-1001-4505)
- Nanxin Gong (ORCID: https://orcid.org/0000-0001-8680-1121)
- Saori Takeyama (ORCID: https://orcid.org/0000-0002-8282-2491)
- Fumikazu Kimura (ORCID: https://orcid.org/0000-0001-7269-2497)
- Keiko Ishii (ORCID: https://orcid.org/0000-0003-0794-746X)
- Takumi Urata (ORCID: https://orcid.org/0009-0001-3512-4527)
- Tomoaki Watanabe (ORCID: https://orcid.org/0000-0002-6015-3717)
Institutions
- Tokyo Institute of Technology (JP)
- Shinshu University (JP)
- National Institute of Information and Communications Technology (JP)
Publication Details
- Journal
- Journal of Medical Imaging
- Published
- 2024-12-28
- DOI
- https://doi.org/10.1117/1.jmi.12.1.017501
- Citations
- 3
- Primary Topic
- Spectroscopy and Chemometric Analyses
- Type
- article
- Field-Weighted Citation Impact
- 0.71