Aerobic exercise improves energy and glucose homeostasis through hypothalamic Mitofusion 2‐rescued endoplasmic reticulum stress in diet‐induced obese mice
These data indicate that aerobic exercise improves whole-body metabolism in DIO mice, probably via increased hypothalamic Mfn2, which could be further mediated by attenuated HFD-induced ER stress in the hypothalamus.
Authors
- Dandong Wu (ORCID: https://orcid.org/0000-0001-8128-0611)
- Linhu Ye (ORCID: https://orcid.org/0000-0002-9200-4409)
- Siyan Zhang (ORCID: https://orcid.org/0000-0002-5326-374X)
- Dingqun Bai (ORCID: https://orcid.org/0000-0002-6727-4634)
- Yi Chen (ORCID: https://orcid.org/0009-0008-3837-5904)
- Renjie Yang
- Hong Chen (ORCID: https://orcid.org/0000-0002-4152-624X)
- Li Jiang (ORCID: https://orcid.org/0000-0002-0865-3511)
Institutions
- Army Medical University (CN)
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Southwest Hospital (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2024-12-26
- DOI
- https://doi.org/10.1111/dom.16120
- Citations
- 3
- Primary Topic
- Endoplasmic Reticulum Stress and Disease
- Type
- article
- Field-Weighted Citation Impact
- 0.98