Effectiveness of switching strategies in <scp>CGRP</scp> monoclonal antibody therapy for migraine: A retrospective cohort study

Switching between anti-CGRP mAbs resulted in a reduction in MHDs, with no significant differences based on the mechanism of action. Factors such as the number of doses of the first mAb and the inter-treatment interval did not appear to predict a ≥50% reduction in MHDs at month 3. Our findings support the viability of switching as an effective treatment option for patients with migraine who do not respond to initial mAb therapy.

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Publication Details

Journal
Headache The Journal of Head and Face Pain
Published
2024-12-27
DOI
https://doi.org/10.1111/head.14865
Citations
10
Primary Topic
Migraine and Headache Studies
Type
article
Field-Weighted Citation Impact
3.86

Funders

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article

Effectiveness of switching strategies in CGRP monoclonal antibody therapy for migraine: A retrospective cohort study

Alex Jaimes, Olga Pajares, Andrea Gómez, Jaime Rodríguez‐Vico
10 citations
Headache The Journal of Head and Face Pain
Migraine and Headache Studies
3.86
article

Effectiveness of switching strategies in CGRP monoclonal antibody therapy for migraine: A retrospective cohort study

Alex Jaimes, Olga Pajares, Andrea Gómez, Jaime Rodríguez‐Vico
article en
10 citations

Abstract

Switching between anti-CGRP mAbs resulted in a reduction in MHDs, with no significant differences based on the mechanism of action. Factors such as the number of doses of the first mAb and the inter-treatment interval did not appear to predict a ≥50% reduction in MHDs at month 3. Our findings support the viability of switching as an effective treatment option for patients with migraine who do not respond to initial mAb therapy.

Headache The Journal of Head and Face PainVol. 65(4)
Hospital Universitario Fundación Jiménez Díaz (ES), Universidad Autónoma de Madrid (ES)
Eli Lilly and Company, Teva Pharmaceutical Industries, Allergan
Good health and well-being
Openalex Percentile: Top 5%
Migraine and Headache Studies
3.86
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