Determinants of growth differentiation factor 15 plasma levels in outpatients with peripheral arterial disease
Circulating GDF-15 is more strongly associated with traditional CV risk factors, especially diabetes, LDL cholesterol, and physical activity than with specific indicators of atherosclerotic burden or cardiac dysfunction. To better understand the pathophysiological role of GDF-15 and its link to clinical outcomes in patients with PAD, future studies should focus on the metabolic processes involved in atherosclerotic disease.
Authors
- Emma Skau (ORCID: https://orcid.org/0000-0002-5625-1146)
- Jerzy Leppert (ORCID: https://orcid.org/0000-0003-1433-0329)
- Pär Hedberg (ORCID: https://orcid.org/0000-0001-5731-966X)
- Johan Ärnlöv (ORCID: https://orcid.org/0000-0002-6933-4637)
- Philippe Wagner (ORCID: https://orcid.org/0000-0002-9293-3371)
Institutions
- Dalarna University (SE)
- Uppsala University (SE)
- Danderyds sjukhus (SE)
- Karolinska Institutet (SE)
- Västmanlands sjukhus Västerås (SE)
Publication Details
- Journal
- Upsala Journal of Medical Sciences
- Published
- 2024-12-27
- DOI
- https://doi.org/10.48101/ujms.v129.11001
- Citations
- 2
- Primary Topic
- GDF15 and Related Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Sveriges Läkarförbund