Combined Sequential Antiretroviral Therapy–Induced Immune Reconstitution Bone Loss and Estrogen Deficiency Bone Loss Are Cumulative in Mice Models
Sequential IRBL and postmenopausal bone loss appear to be cumulative. If validated in humans, early screening and prophylaxis could reduce fracture risk in postmenopausal women with HIV. Probiotic therapy may provide a beneficial alternative to pharmacotherapy.
Authors
- Ashish Kumar Tripathi (ORCID: https://orcid.org/0000-0002-0976-8476)
- Tatyana Vikulina
- Sadaf Dabeer (ORCID: https://orcid.org/0000-0002-0564-4185)
- M. Neale Weitzmann (ORCID: https://orcid.org/0000-0003-3305-5748)
- Ighovwerha Ofotokun (ORCID: https://orcid.org/0000-0003-2735-1903)
- Daiana Weiss
Institutions
- Emory University (US)
- Grady Health System (US)
- St. Joseph Health System (US)
- Atlanta VA Health Care System (US)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2024-12-27
- DOI
- https://doi.org/10.1093/infdis/jiae643
- Citations
- 2
- Primary Topic
- HIV-related health complications and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.38