Characterization of craniofacial tissue aging in genetically diverse HET3 male mice with longevity treatment of 17-alpha estradiol
The HET3 mice present an excellent model with which to study the heterogeneous nature of tooth aging and the effects of longevity interventions. We provide novel data on how 17αE2 improves healthspan by modifying age-related changes in the molar dentin and cementum of male mice.
Authors
- Jake W. Willows (ORCID: https://orcid.org/0000-0002-9695-6642)
- Sarah B. Peters (ORCID: https://orcid.org/0000-0003-3384-5109)
- Kristy L. Townsend (ORCID: https://orcid.org/0000-0002-2849-9195)
- Rami Alsabbagh
- Leah LaVerde
- Emma Chufar
Institutions
- The Ohio State University (US)
Publication Details
- Journal
- Archives of Oral Biology
- Published
- 2024-12-27
- DOI
- https://doi.org/10.1016/j.archoralbio.2024.106170
- Primary Topic
- Genetics, Aging, and Longevity in Model Organisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Heart Association
- National Institutes of Health
- National Institute of Dental and Craniofacial Research