HYPOTHERMIC MASHINE PERFUSION AS A TOOL OF PROLONGATION OF SAFE COLD ISCHEMIA TIME IN KIDNEY TRANSPLANTATION. CASE REPORT

Introduction. Hypothermic machine perfusion (HMP) is an effective tool for organ protection against ischemia-reperfusion injury. However, we have not enough clear data about duration of safe cold ischemia time in a case of kidney transplantation with using HMP. We present a case of the first in Ukraine using of HMP in a case of deceased donor kidney transplantation as an example of role of HMP in the extending the logistic capabilities of transplant center. Case report. Deceased donor kidney transplantation was performed in transplant center in Lviv. Graft was procured in Odesa. Due to long ischemic time HMP was used. Cold ischemic time was 23.5 hours, but no symptoms of ischemia-reperfusion injury were detected. The postoperative period passed without complication. Conclusion. Cold ischemia time of about 24 hours with using HMP may be safe, but its issue requires further research.

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Publication Details

Journal
Pain anesthesia and intensive care
Published
2024-11-28
DOI
https://doi.org/10.25284/2519-2078.4(109).2024.318726
Primary Topic
Organ Transplantation Techniques and Outcomes
Type
article
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article

HYPOTHERMIC MASHINE PERFUSION AS A TOOL OF PROLONGATION OF SAFE COLD ISCHEMIA TIME IN KIDNEY TRANSPLANTATION. CASE REPORT

N.V. Matolinets, О.О. Samchuk, Oleksandr Shchur, Maksym Ovechko et al.
Pain anesthesia and intensive care
Organ Transplantation Techniques and Outcomes
article

HYPOTHERMIC MASHINE PERFUSION AS A TOOL OF PROLONGATION OF SAFE COLD ISCHEMIA TIME IN KIDNEY TRANSPLANTATION. CASE REPORT

N.V. Matolinets, О.О. Samchuk, Oleksandr Shchur, Maksym Ovechko, Volodymyr Diatel
article en

Abstract

Introduction. Hypothermic machine perfusion (HMP) is an effective tool for organ protection against ischemia-reperfusion injury. However, we have not enough clear data about duration of safe cold ischemia time in a case of kidney transplantation with using HMP. We present a case of the first in Ukraine using of HMP in a case of deceased donor kidney transplantation as an example of role of HMP in the extending the logistic capabilities of transplant center. Case report. Deceased donor kidney transplantation was performed in transplant center in Lviv. Graft was procured in Odesa. Due to long ischemic time HMP was used. Cold ischemic time was 23.5 hours, but no symptoms of ischemia-reperfusion injury were detected. The postoperative period passed without complication. Conclusion. Cold ischemia time of about 24 hours with using HMP may be safe, but its issue requires further research.

Pain anesthesia and intensive care(4(109))
Danylo Halytsky Lviv National Medical University (UA)
Good health and well-being
Openalex Percentile: Top 55%
Organ Transplantation Techniques and Outcomes
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