Pediatric Bell’s Palsy: Prognostic Factors, Management Strategy, and Treatment Outcomes

<b>Background/Objectives:</b> Bell's palsy (BP) is a neurological disorder characterized by sudden unilateral peripheral facial paralysis. The etiology in children remains largely unknown, and standardized management strategies are lacking. The aim of this retrospective cohort study is to evaluate clinical features, laboratory markers, and therapeutic options associated with recovery to identify potential prognostic factors and validate therapeutic strategies, with a particular focus on the role of corticosteroids and vitamin supplementation. <b>Methods:</b> A retrospective cohort study was conducted on 88 children (aged < 18 years) diagnosed with BP at a single tertiary care center between 2010 and 2023. Clinical data, including House-Brackmann (HB) scores, were collected at baseline and at a two-month follow-up. Statistical analysis was performed to assess the associations between demographic, clinical, and laboratory parameters with recovery outcomes. Prednisone and vitamin supplementation were administered at the discretion of the treating pediatrician. <b>Results:</b> In total, 81.8% of patients achieved complete recovery at 2-month follow-up (HB grade 1). No significant associations were found between recovery and gender, age, side of paralysis, initial HB grade, or laboratory markers. However, the use of prednisone was associated with a higher rate of incomplete recovery (<i>p</i> = 0.024), with higher doses correlating with poorer outcomes (<i>p</i> = 0.022). Vitamin supplementation showed no significant impact. <b>Conclusions:</b> Our findings suggest that corticosteroid therapy may not be a disease-modifying factor that ultimately influences outcomes in pediatric BP. Further large-scale studies are needed to define evidence-based protocols for managing pediatric BP.

Authors

Institutions

Publication Details

Journal
Journal of Clinical Medicine
Published
2024-12-27
DOI
https://doi.org/10.3390/jcm14010079
Citations
3
Primary Topic
Facial Nerve Paralysis Treatment and Research
Type
article
Field-Weighted Citation Impact
1.11
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Pediatric Bell’s Palsy: Prognostic Factors, Management Strategy, and Treatment Outcomes

Antonio Gatto, Valeria Pansini, Francesco Andrea Causio, Benedetta Graglia et al.
3 citations
Journal of Clinical Medicine
Facial Nerve Paralysis Treatment and Research
1.11
article

Pediatric Bell’s Palsy: Prognostic Factors, Management Strategy, and Treatment Outcomes

Antonio Gatto, Valeria Pansini, Francesco Andrea Causio, Benedetta Graglia, Lorenzo Di Sarno, Antonio Chiaretti, Anya Caroselli, Natalia Camilla Di Vizio
article en
3 citations

Abstract

<b>Background/Objectives:</b> Bell's palsy (BP) is a neurological disorder characterized by sudden unilateral peripheral facial paralysis. The etiology in children remains largely unknown, and standardized management strategies are lacking. The aim of this retrospective cohort study is to evaluate clinical features, laboratory markers, and therapeutic options associated with recovery to identify potential prognostic factors and validate therapeutic strategies, with a particular focus on the role of corticosteroids and vitamin supplementation. <b>Methods:</b> A retrospective cohort study was conducted on 88 children (aged < 18 years) diagnosed with BP at a single tertiary care center between 2010 and 2023. Clinical data, including House-Brackmann (HB) scores, were collected at baseline and at a two-month follow-up. Statistical analysis was performed to assess the associations between demographic, clinical, and laboratory parameters with recovery outcomes. Prednisone and vitamin supplementation were administered at the discretion of the treating pediatrician. <b>Results:</b> In total, 81.8% of patients achieved complete recovery at 2-month follow-up (HB grade 1). No significant associations were found between recovery and gender, age, side of paralysis, initial HB grade, or laboratory markers. However, the use of prednisone was associated with a higher rate of incomplete recovery (<i>p</i> = 0.024), with higher doses correlating with poorer outcomes (<i>p</i> = 0.022). Vitamin supplementation showed no significant impact. <b>Conclusions:</b> Our findings suggest that corticosteroid therapy may not be a disease-modifying factor that ultimately influences outcomes in pediatric BP. Further large-scale studies are needed to define evidence-based protocols for managing pediatric BP.

Journal of Clinical MedicineVol. 14(1)
Università Cattolica del Sacro Cuore (IT), Agostino Gemelli University Polyclinic (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT)
No poverty
Openalex Percentile: Top 20%
Facial Nerve Paralysis Treatment and Research
1.11
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.