Case report – Muir–Torre syndrome – A skin-deep manifestation of underlying malignancy

We report a case of Muir–Torre syndrome in an Indian male patient diagnosed with synchronous malignancy of squamous cell carcinoma and adenocarcinoma colon, with a strong family history of gastrointestinal malignancies. Next-generation sequencing revealed germline mutations in Mut S homolog 6. Skin tumors particularly sebaceous carcinoma, sebaceous adenoma, squamous cell carcinoma, and keratoacanthoma serve as cutaneous markers for internal malignancy.