Infantile Hemangioma With Aggressive, Early‐Onset Ulceration, and Kasabach–Merritt‐Like Phenomenon in a Newborn

Infantile hemangiomas (IH) are the most common benign tumors of infancy and progress through recognized stages of evolution including early proliferation, plateau, and involution. Ulceration is a common complication of IHs typically observed during the early proliferative stage characterized by rapid growth. In rare cases, ulceration is the primary clinical manifestation of IHs. We present the case of a newborn with an IH manifesting as an aggressive, early-onset ulcerative lesion on the lower extremity associated with transient thrombocytopenia and coagulation abnormalities.

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Publication Details

Journal
Pediatric Dermatology
Published
2024-12-27
DOI
https://doi.org/10.1111/pde.15836
Primary Topic
Vascular Malformations and Hemangiomas
Type
article
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article

Infantile Hemangioma With Aggressive, Early‐Onset Ulceration, and Kasabach–Merritt‐Like Phenomenon in a Newborn

Jason B. Lee, Ngan Do, Robert J. Smith, Sherry Yang et al.
Pediatric Dermatology
Vascular Malformations and Hemangiomas
article

Infantile Hemangioma With Aggressive, Early‐Onset Ulceration, and Kasabach–Merritt‐Like Phenomenon in a Newborn

Jason B. Lee, Ngan Do, Robert J. Smith, Sherry Yang, María Trinidad Hasbún, Albert C. Yan, Robert Duffy, Charles Huang, Marissa J. Perman, Maria Queenan, Supriya Rastogi
article en

Abstract

Infantile hemangiomas (IH) are the most common benign tumors of infancy and progress through recognized stages of evolution including early proliferation, plateau, and involution. Ulceration is a common complication of IHs typically observed during the early proliferative stage characterized by rapid growth. In rare cases, ulceration is the primary clinical manifestation of IHs. We present the case of a newborn with an IH manifesting as an aggressive, early-onset ulcerative lesion on the lower extremity associated with transient thrombocytopenia and coagulation abnormalities.

Pediatric DermatologyVol. 42(3)
Children's Hospital of Philadelphia (US), Universidad del Desarrollo (CL), Thomas Jefferson University (US), Thomas Jefferson University Hospital (US), Clínica Alemana (CL), University of Pennsylvania (US)
Good health and well-being
Openalex Percentile: Top 55%
Vascular Malformations and Hemangiomas
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Infantile Hemangioma With Aggressive, Early‐Onset Ulceration, and Kasabach–Merritt‐Like Phenomenon in a Newborn — Jason B. Lee, Ngan Do, et al. · Pediatric Dermatology (2024) | TGRS Research Map | TGRS