<i>KRAS</i>Mutations in Cholangiocarcinoma: Prevalence, Prognostic Value, and<i>KRAS</i>G12/G13 Detection in Cell-Free DNA
The presence of KRAS mutations was associated with poor survival in CCA, underscoring the importance of KRAS mutations as prognostic markers. The detection of KRAS mutations in cfDNA demonstrated potential as a promising non-invasive alternative for mutation detection and, when combined with CA19-9 levels, may improve prognostic efficacy in CCA.
Authors
- Anchalee Techasen (ORCID: https://orcid.org/0000-0002-4230-5641)
- Piyapharom Intarawichian (ORCID: https://orcid.org/0000-0002-0181-5573)
- Chaiwat Aphivatanasiri (ORCID: https://orcid.org/0000-0001-9185-4121)
- Watcharin Loilome (ORCID: https://orcid.org/0000-0001-8572-5577)
- Waritta Kunprom
- Apinya Jusakul (ORCID: https://orcid.org/0000-0001-7652-7771)
- Nisana Namwat (ORCID: https://orcid.org/0000-0002-6743-5047)
- Sarinya Kongpetch (ORCID: https://orcid.org/0000-0001-9767-4906)
- Jarin Chindaprasirt (ORCID: https://orcid.org/0000-0002-0401-9812)
- Attapol Titapun (ORCID: https://orcid.org/0000-0002-2228-752X)
- PITCHASAK THONGYOO
Institutions
- Khon Kaen University (TH)
Publication Details
- Journal
- Cancer Genomics & Proteomics
- Published
- 2024-12-27
- DOI
- https://doi.org/10.21873/cgp.20492
- Citations
- 11
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 6.30
Funders
- Khon Kaen University
- Ministry of Higher Education, Science, Research and Innovation, Thailand
- Thailand Science Research and Innovation
- Cholangiocarcinoma Research Institute, Khon Kaen University