Reaction of Tetrahydropyrimidine-2(1<i>H</i>)-thione Derivatives with Thiolated Acid Hydrazides as a Method of Synthesis of Biologically Active Ligands of Gold Glyco-Nanoparticles
The reaction of 4-hydroxy-1-phenyl-6-methyltetrahydropyrimidine-2(1H)-thione with 6-mercaptohexanoic and lipoic (thioctic) acids hydrazides in yields of 60–75% to form 4-[ω-(mercaptoacyl)hydrazino]-tetrahydropyrimidine-2(1H)-thiones as a promising сo-ligands for the preparation of gold glyco-nanoparticles for biomedical purposes.
Authors
- А. А. Мартыненков (ORCID: https://orcid.org/0000-0002-0951-1451)
- А. Yu. Ershov (ORCID: https://orcid.org/0000-0002-2266-4380)
- A. A. Batyrenko (ORCID: https://orcid.org/0000-0001-9688-3650)
- И. В. Лагода (ORCID: https://orcid.org/0000-0002-3906-2909)
Institutions
- Institute of Macromolecular Compounds (RU)
Publication Details
- Journal
- Журнал органической химии
- Published
- 2024-12-27
- DOI
- https://doi.org/10.31857/s0514749224020041
- Primary Topic
- Synthesis and Characterization of Heterocyclic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 0.00