Fetal and maternal outcomes of gestational thrombocytopenia: an observational study

Background: The most common cause of pregnancy-related thrombocytopenia is gestational thrombocytopenia. There is a paucity of studies showing the effect of GT in mothers and neonates in the Indian population. So the present study was done to find out maternal and fetal outcomes of gestational thrombocytopenia in a tertiary care centre. Methods: 92 pregnant women diagnosed with gestational thrombocytopenia with platelet count of less than 150000 were enrolled. Women with hypertensive disorders, autoimmune diseases, acute and chronic kidney disease, infections like dengue fever were excluded. The participants were evaluated by taking detailed history, clinical examination and routine investigations like complete blood count. Demographic variables like age, parity and clinical details like when she was diagnosed with gestational thrombocytopenia and what was the platelet count were noted. Complete blood count-platelets were measured at the time of diagnosis. Patients were followed through the pregnancy until delivery, various maternal factors were observed like oligohydramnios, IUGR, Antepartum hemorrhage, mode of delivery, post-delivery complications like PPH, incision site hematoma. Neonatal outcomes studied were APGAR, birth weight, neonatal thrombocytopenia and NICU admission. Results: There was no positive correlation between mothers with gestational thrombocytopenia and adverse maternal, neonatal outcomes (age, liquor abnormalities, IUGR, mode of delivery, APH, PPH, incision hematoma, neonatal thrombocytopenia, APGAR, birth weight, NICU admissions). Conclusions: It’s concluded that women with gestational thrombocytopenia do not have any adverse antenatal, perinatal, intrapartum, postnatal and neonatal complications.

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Publication Details

Journal
International Journal of Reproduction Contraception Obstetrics and Gynecology
Published
2024-12-27
DOI
https://doi.org/10.18203/2320-1770.ijrcog20243927
Primary Topic
Platelet Disorders and Treatments
Type
article
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article

Fetal and maternal outcomes of gestational thrombocytopenia: an observational study

Karthikeyan Kadirvel, Lopamudra B. John, Tapasvi Kadiyala
International Journal of Reproduction Contraception Obstetrics and Gynecology
Platelet Disorders and Treatments
article

Fetal and maternal outcomes of gestational thrombocytopenia: an observational study

Karthikeyan Kadirvel, Lopamudra B. John, Tapasvi Kadiyala
article en

Abstract

Background: The most common cause of pregnancy-related thrombocytopenia is gestational thrombocytopenia. There is a paucity of studies showing the effect of GT in mothers and neonates in the Indian population. So the present study was done to find out maternal and fetal outcomes of gestational thrombocytopenia in a tertiary care centre. Methods: 92 pregnant women diagnosed with gestational thrombocytopenia with platelet count of less than 150000 were enrolled. Women with hypertensive disorders, autoimmune diseases, acute and chronic kidney disease, infections like dengue fever were excluded. The participants were evaluated by taking detailed history, clinical examination and routine investigations like complete blood count. Demographic variables like age, parity and clinical details like when she was diagnosed with gestational thrombocytopenia and what was the platelet count were noted. Complete blood count-platelets were measured at the time of diagnosis. Patients were followed through the pregnancy until delivery, various maternal factors were observed like oligohydramnios, IUGR, Antepartum hemorrhage, mode of delivery, post-delivery complications like PPH, incision site hematoma. Neonatal outcomes studied were APGAR, birth weight, neonatal thrombocytopenia and NICU admission. Results: There was no positive correlation between mothers with gestational thrombocytopenia and adverse maternal, neonatal outcomes (age, liquor abnormalities, IUGR, mode of delivery, APH, PPH, incision hematoma, neonatal thrombocytopenia, APGAR, birth weight, NICU admissions). Conclusions: It’s concluded that women with gestational thrombocytopenia do not have any adverse antenatal, perinatal, intrapartum, postnatal and neonatal complications.

International Journal of Reproduction Contraception Obstetrics and GynecologyVol. 14(1)
Mahatma Gandhi Medical College and Research Institute (IN), Mahatma Gandhi Medical College and Research Institute (IN)
Good health and well-being
Openalex Percentile: Top 56%
Platelet Disorders and Treatments
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Fetal and maternal outcomes of gestational thrombocytopenia: an observational study — Karthikeyan Kadirvel, Lopamudra B. John, et al. · International Journal of Reproduction Contraception Obstetrics and Gynecology (2024) | TGRS Research Map | TGRS