Evaluation of long axial field-of-view (LAFOV) PET/CT for post-treatment dosimetry in Yttrium-90 radioembolization of liver tumors: a comparative study with conventional SPECT imaging
LAFOV PET enabled the direct measurement of post therapy lung dose and tumor doses that correlated well with the planned treatment doses. However, current voxel-wise-based tumor dosimetry seems to be inaccurate for LAFOV PET. In addition, dose volume histogram-based metrics also significantly underestimate the delivered dose. Therefore, improved dosimetry tools are needed for reliable voxel-wise <sup>90</sup>Y dosimetry to leverage the sensitivity and spatial resolution of LAFOV PET scanners.
Authors
- Hasan Sari (ORCID: https://orcid.org/0000-0002-1504-1767)
- Robert Seifert (ORCID: https://orcid.org/0000-0001-5985-7701)
- Marc Schindewolf (ORCID: https://orcid.org/0000-0003-4597-0759)
- Ali Afshar‐Oromieh (ORCID: https://orcid.org/0000-0002-4492-4243)
- Nasir Gözlügöl
- Axel Rominger (ORCID: https://orcid.org/0000-0002-1954-736X)
- Konstantinos Zeimpekis (ORCID: https://orcid.org/0000-0003-2769-7533)
- Kuangyu Shi (ORCID: https://orcid.org/0000-0002-8714-3084)
- Ngwe Rawlings Achangwa (ORCID: https://orcid.org/0009-0000-1300-6426)
Institutions
- University of Bern (CH)
- University Hospital of Bern (CH)
- Siemens (Switzerland) (CH)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2024-12-28
- DOI
- https://doi.org/10.1007/s00259-024-07034-9
- Citations
- 3
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 1.11