Construction and validation of a nomogram model to predict bronchiolitis Mycoplasma pneumoniae pneumonia in children

After the cancellation of COVID-19 epidemic control measures in 2023, cases of pediatric bronchiolitis caused by Mycoplasma pneumoniae (MP) have been reported successively, with some children experiencing residual bronchiolitis obliterans (BO). Currently, the diagnosis of bronchiolitis Mycoplasma pneumoniae pneumonia (MPP) primarily relies on high-resolution computed tomography (HRCT). To establish a predictive model for bronchiolitis MPP, a retrospective analysis was conducted. The patients were randomly divided into a training cohort and a validation cohort. The nomogram model was constructed in the training cohort. Finally, the differential, calibration, and clinical applicability of the prediction model were evaluated using both the training and validation cohorts. Logistic stepwise regression analysis identified age, atopy, wheezing, hypoxemia, and pleural effusion as independent predictors of bronchiolitis MPP. These factors were used to construct a nomogram model. This nomogram model serves as a useful tool for predicting the risk of bronchiolitis MPP, which may facilitate individualized early intervention.

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Publication Details

Journal
Scientific Reports
Published
2024-12-28
DOI
https://doi.org/10.1038/s41598-024-80906-0
Primary Topic
Respiratory viral infections research
Type
article
Field-Weighted Citation Impact
0.00

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article

Construction and validation of a nomogram model to predict bronchiolitis Mycoplasma pneumoniae pneumonia in children

Jie Peng, Yungang Yang, Qihong Chen, Lihua Lin et al.
Scientific Reports
Respiratory viral infections research
article

Construction and validation of a nomogram model to predict bronchiolitis Mycoplasma pneumoniae pneumonia in children

Jie Peng, Yungang Yang, Qihong Chen, Lihua Lin, Shuping Xiong
article en

Abstract

After the cancellation of COVID-19 epidemic control measures in 2023, cases of pediatric bronchiolitis caused by Mycoplasma pneumoniae (MP) have been reported successively, with some children experiencing residual bronchiolitis obliterans (BO). Currently, the diagnosis of bronchiolitis Mycoplasma pneumoniae pneumonia (MPP) primarily relies on high-resolution computed tomography (HRCT). To establish a predictive model for bronchiolitis MPP, a retrospective analysis was conducted. The patients were randomly divided into a training cohort and a validation cohort. The nomogram model was constructed in the training cohort. Finally, the differential, calibration, and clinical applicability of the prediction model were evaluated using both the training and validation cohorts. Logistic stepwise regression analysis identified age, atopy, wheezing, hypoxemia, and pleural effusion as independent predictors of bronchiolitis MPP. These factors were used to construct a nomogram model. This nomogram model serves as a useful tool for predicting the risk of bronchiolitis MPP, which may facilitate individualized early intervention.

Scientific ReportsVol. 14(1)
Fujian Medical University (CN), First Affiliated Hospital of Xiamen University (CN)
Xiamen University
Openalex Percentile: Top 64%
Respiratory viral infections research
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