Genetic Association of Juvenile Idiopathic Arthritis With Adult Rheumatic Disease
In this genetic association study, there was significant genetic overlap between JIA and adult rheumatic diseases. These findings may help to refine JIA classification, risk stratification, and therapeutic strategy of repurposing adult disease drugs for pediatric patients with similar mechanisms.
Authors
- Qianghua Xia (ORCID: https://orcid.org/0000-0002-0177-4361)
- Yan Fu (ORCID: https://orcid.org/0000-0002-4942-159X)
- Jin Li (ORCID: https://orcid.org/0000-0001-7024-3591)
- Shuzhong Cui (ORCID: https://orcid.org/0000-0003-2178-8741)
- Gang Zheng (ORCID: https://orcid.org/0000-0003-0276-9430)
- Jian Hao (ORCID: https://orcid.org/0000-0002-4403-8188)
- Joseph Glessner (ORCID: https://orcid.org/0000-0001-5131-2811)
- Hui‐Qi Qu (ORCID: https://orcid.org/0000-0001-9317-4488)
- Wei Wei (ORCID: https://orcid.org/0000-0002-4386-8577)
- Xiaoyang Liu (ORCID: https://orcid.org/0000-0002-1202-6764)
- Wei Liu (ORCID: https://orcid.org/0000-0002-9302-8170)
- Zhiyong Ding
- Dandan Ji (ORCID: https://orcid.org/0009-0004-4863-9193)
- Jingxian Fan
- Hakon Hakonarson
Institutions
- Children's Hospital of Philadelphia (US)
- Tianjin University (CN)
- Tianjin Medical University General Hospital (CN)
- Tianjin Children's Hospital (CN)
- National Supercomputing Center of Tianjin (CN)
- Tianjin Medical University (CN)
- University of Pennsylvania (US)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2024-12-27
- DOI
- https://doi.org/10.1001/jamanetworkopen.2024.51341
- Citations
- 5
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 2.27